High prevalence of deleterious BRCA1 and BRCA2 germline mutations in arab breast and ovarian cancer patients.

Al-Joharah AlhuqailAreej AlzahraniHannah AlmubarakSarah Al-QadheebLamyaa AlghofailiNisreen AlmoghrabiHamed AlhussainiBen Ho ParkDilek ColakBedri Karakas

Published in: Breast cancer research and treatment (2018)

The overall frequencies of the BRCA germline mutations were 10.2% in breast and 30.7% in ovarian cancer patients. These data shed new light into the prevalence of BRCA mutations in the Arab women population.

Keyphrases

breast cancer risk
dna repair
risk factors
polycystic ovary syndrome
type diabetes
big data
skeletal muscle
adipose tissue
metabolic syndrome
artificial intelligence
deep learning
insulin resistance