Longitudinally Extensive Myelitis Associated With Immune Checkpoint Inhibitors.
Alberto PiccaGiulia BerzeroKevin BihanVincent JachietEdouard JanuelMarc CoustansCecile CauquilJulie PerrinPablo BerlangaNora KramkimelBethsabée GarelPerrine DevicFrançois DucrayMarion BenazraFlavie BompaireDelphine LeclercqJean Marie MichotSamy AmmariDimitri PsimarasPublished in: Neurology(R) neuroimmunology & neuroinflammation (2021)
Myelitis is a rare but severe complication of ICIs that shows limited response to glucocorticoids. Considering the poor functional outcome associated with longitudinally extensive myelitis, strong and protracted immune therapy combinations are probably needed upfront to improve patient outcome and prevent early relapses.