Comprehensive characterization of viral integrations and genomic aberrations in HBV-infected intrahepatic cholangiocarcinomas.
Jihyun AnDeokhoon KimBora OhYoo-Jin OhJihyun SongNaomi ParkHa Il KimHyo Jeong KangJi-Hye OhWonkyung KimEunjung LeeChang Ohk SungGi-Won SongDae-Ghon KimEunsil YuEric LetouzéJessica Zucman-RossiHan Chu LeeJu Hyun ShimPublished in: Hepatology (Baltimore, Md.) (2021)
Our findings provide insight into the behavior of iCCAs driven by various pathogenic mechanisms involving HBV integration events and associated genomic aberrations. This knowledge should be of use in managing HBV carriers.