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Glutamate ionotropic receptor NMDA type subunit 2A (GRIN2A) gene polymorphism (rs4998386) and Parkinson's disease susceptibility: A meta-analysis.

Gaurav NepalJessica Holly RehrigRajeev Ojha
Published in: Aging medicine (Milton (N.S.W)) (2019)
Our meta-analysis found that the rs4998386 polymorphism of the GRIN2A gene is not associated with risk of PD in either Europeans or white Americans. However, large sample studies with different ethnicities should be conducted to establish the role of the rs4998386 polymorphism in PD pathophysiology.
Keyphrases
  • systematic review
  • case control
  • meta analyses
  • copy number
  • genome wide
  • protein kinase