The distinct hepatic metabolic profile and relation with impaired liver function in congenital isolated growth hormone-deficient rats.

Xiaonan GuoWenjing HuXiaorui LyuHanyuan XuHuijuan ZhuHui PanLinjie WangHongbo Yang Fengying Gong

Published in: Endocrine connections (2024)

Lewis dw/dw rats with congenital isolated growth hormone deficiency (IGHD) showed liver steatosis and abnormal liver function, which could be potentially associated with the distinctive hepatic metabolic profiles.

Keyphrases

growth hormone
insulin resistance
type diabetes
metabolic syndrome
replacement therapy
high fat diet induced