Sex-dependent vulnerability for Wistar rats model following intranasal instillation with Klebsiella pneumoniae ATCC 43816 causing lobar pneumonia.

Patrick Hervé Diboue BetoteEsther Del Florence Ndedi MoniSonia Raïssa Gayap MatchuenkamSandrine Suzanne Bayengue BeackRodrigue FifenRaogo OuedraogoGabriel A AgborRasmané SemdeNga NnangaMaximilienne Ascension Nyegue

Published in: Pneumonia (Nathan Qld.) (2024)

The results obtained highlighted the gender-dependency in the physiopathogenesis processes of K. pneumoniae ATCC 43816 induced-lobar pneumonia, in Wistar rats. Female Wistar rats' susceptibility is useful in studying pathology and in preclinical trial investigations of new treatments for infectious pneumonia.

Keyphrases

klebsiella pneumoniae
multidrug resistant
escherichia coli
respiratory failure
community acquired pneumonia
study protocol
clinical trial
high glucose
mental health
diabetic rats
stem cells
phase iii
intensive care unit
drug induced
endothelial cells
mechanical ventilation