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PCR-based zebrafish model for personalised medicine in head and neck cancer.

Ahmed Al-SamadiKatja TuomainenAnne KivimäkiAbdelhakim SalemSakhr Al-KubatiAini HyytiäinenMataleena ParikkaKarri MesimäkiTommy WilkmanAntti MäkitieReidar GrenmanTuula Salo
Published in: Journal of translational medicine (2019)
We introduce a novel, easy, fast and cost-effective PCR-based in vivo zebrafish larvae assay to test the response of cell lines and clinical tumour samples to anti-cancer drugs. This method goes hand-by-hand with the commonly used imaging assay.
Keyphrases
  • high throughput
  • high resolution
  • real time pcr
  • drosophila melanogaster