Clinical value of liquid biopsy in FGFR2 fusion-positive cholangiocarcinoma patients during targeted therapy.
Alberto Gonzalez-MedinaMaria Vila-CasadesúsMarina Gómez-ReyCarles Fabregat-FrancoAlexandre SierraTian V TianFlorian CastetGloria CastilloJudit MatitoPaola MartinezJosep M MiquelPaolo G NuciforoRaquel Perez-LopezTeresa MacarullaAna VivancosPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
VHIO-iCCA demonstrated accurate detection of FGFR2 fusions in plasma. The integration of information from various plasma biomarkers holds the potential to predict clinical outcomes and identify treatment failure prior to radiological progression, offering valuable guidance for the clinical management of patients with iCCA.