Investigating the effects of a single ASPM variant (c.8508_8509) on brain architecture among siblings in a consanguineous Pakistani family.
Komal AslamAysha SaeedIffat JamilHafiza Iqra SaeedRamisha KhanSamina HassanShereen RafiqMaria AsifEhtisham Ul Haq MakhdoomRasheeda BashirMuhammad Sajid HussainShahid Mahmood BaigIram AnjumPublished in: Molecular biology reports (2024)
This study explores the extraordinary influence of a single ASPM variant on divergent brain structure in consanguineous siblings and enable us to reduce the incidence of further microcephalic cases in this Pakistani family (Aslam et al. in Kinnaird's 2nd International Conference on Science, Technology and Innovation, Lahore, 2023).