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hmmIBD: software to infer pairwise identity by descent between haploid genotypes.

Stephen F SchaffnerAimee R TaylorWesley WongDyann F WirthDaniel E Neafsey
Published in: Malaria journal (2018)
Fast and accurate software for detecting IBD in malaria parasite genetic data sampled from one or two populations is presented. The latter will likely be a useful feature for malaria elimination efforts, since it could facilitate identification of imported malaria cases. Software is robust to possible misspecification of the genotyping error and the recombination rate. However, exclusion of data in regions whose rates vary greatly from their genome-wide average is recommended.
Keyphrases
  • plasmodium falciparum
  • genome wide
  • data analysis
  • dna methylation
  • electronic health record
  • copy number
  • big data
  • machine learning
  • dna damage
  • high throughput
  • oxidative stress
  • single cell