Toward Improving Patients' Experiences of Acute Toxicity From Breast Radiotherapy: Insights From the Analysis of Patient-Reported Outcomes in a Large Multicenter Cohort.
Reshma JagsiKent A GriffithFrank ViciniThomas BoikeJacob BurmeisterMichael M DominelloInga GrillsJames A HaymanJean M MoranPeter PaximadisJeffrey D RadawskiEleanor M WalkerLori J Piercenull nullPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2020)
In this large observational data set, substantial differences existed according to radiotherapy dose fractionation. Race-related differences in pain existed despite controlling for multiple other factors; additional research is needed to understand what drives these differences to target potentially modifiable factors. Intensifying supportive care may be appropriate for subgroups identified as being vulnerable to greater toxicity.
Keyphrases
- patient reported outcomes
- early stage
- end stage renal disease
- locally advanced
- healthcare
- ejection fraction
- radiation therapy
- newly diagnosed
- oxidative stress
- chronic pain
- pain management
- radiation induced
- liver failure
- palliative care
- chronic kidney disease
- prognostic factors
- intensive care unit
- neuropathic pain
- drug induced
- peritoneal dialysis
- clinical trial
- rectal cancer
- respiratory failure
- patient reported
- spinal cord
- double blind
- oxide nanoparticles
- aortic dissection
- deep learning