The Glycocalyx and Pressure-Dependent Transcellular Albumin Transport.
Randal O DullAndreia Zago ChignaliaPublished in: Cardiovascular engineering and technology (2020)
Pressure-dependent albumin uptake and transcellular transport is another component of endothelial mechanotransduction and associated regulation of solute flux. This novel albumin uptake and transport pathway is regulated by heparan sulfates and eNOS. Albumin uptake is sensitive to ROS. The physiological and clinical implications of this albumin transport are discussed.