A novel bioreactor for combined magnetic resonance spectroscopy and optical imaging of metabolism in 3D cell cultures.

Benjamin L CoxSarah Erickson-BhattJoseph M SzulczewskiJayne M SquirrellKai D LudwigErin B MacdonaldRobert SwaderSuzanne M PonikKevin W Eliceiri Sean B Fain

Published in: Magnetic resonance in medicine (2019)

A novel bioreactor that is compatible with, and can exploit the benefits of, both FLIM and 13 C MRS in 3D cell cultures for studies of cell metabolism has been designed and applied.

Keyphrases

single cell
cell therapy
high resolution
wastewater treatment
mesenchymal stem cells
bone marrow
mass spectrometry