A combined intrapleural administration of dornase alfa and tissue plasminogen activator is safe in children with empyema - A pilot study.
Monique A SlaatsJozef De DooyKim Van HoorenbeeckPaul E Y Van SchilStijn L VerhulstJeroen M H HendriksPublished in: Acta chirurgica Belgica (2019)
The intrapleural treatment of dornase alfa and tissue plasminogen activator as treatment of empyema was safe in ten children with empyema. If confirmed in further studies, this combination of intrapleural therapy may improve the management of pediatric empyema.