Detection of clinically significant prostate cancer in biopsy-naïve men: direct comparison of systematic biopsy, multiparametric MRI- and contrast-ultrasound-dispersion imaging-targeted biopsy.
Christophe K MannaertsMarc R W EngelbrechtArnoud W PostemaRob A A van KollenburgCaroline M A HoeksCemile Dilara Savci-HeijinkRuud J G van SlounRogier R WildeboerTheo M De ReijkeMassimo MischiHessel WijkstraPublished in: BJU international (2020)
In our study in biopsy-naïve men, the mpMRI- and CUDI-TBx strategies had comparable PCa detection rates, but the mpMRI-TBX strategy had the least false-positive findings. Both strategies were inferior to SBx for the detection of GG ≥2 PCa, despite reduced detection of insignificant GG = 1 PCa. Both strategies did not significantly differ from SBx for the detection of GG ≥2 PCa with CR/IDC and GG ≥3 PCa.