Quantitative proteomic analyses of CD4+ and CD8+ T cells reveal differentially expressed proteins in multiple sclerosis patients and healthy controls.

Tone BergeAnna ErikssonIna Skaara BrorsonEinar August HøgestølPål Berg-HansenAnne DøskelandOlav MjaavattenSteffan Daniel BosHanne F HarboFrode Berven

Published in: Clinical proteomics (2019)

Our study provides evidence for proteomic differences in T cells from relapsing-remitting MS patients compared to healthy controls and also identifies dysregulation of proteins encoded from MS susceptibility genes.

Keyphrases

multiple sclerosis
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
mass spectrometry
prognostic factors
genome wide
peritoneal dialysis
rheumatoid arthritis
systemic lupus erythematosus
disease activity
single cell
genome wide identification
bioinformatics analysis