miR663 Prevents Epo Inhibition Caused by TNF-Alpha in Normoxia and Hypoxia.

Mete Ozkurt Thomas Hellwig-Bürgel Reinhard Depping Selda Kadabere Rumeysa Özyurt Abdullah Karadag Nilufer Erkasap

Published in: International journal of endocrinology (2021)

miR663 is involved in Epo mRNA production and that is able to prevent or reverse the inhibitory effect of TNF-α. In our coculture study, transfecting HepG2 cells with miR663 mimics decreased the apoptosis of UT-7 cells.

Keyphrases

cell proliferation
long non coding rna
cell cycle arrest
long noncoding rna
rheumatoid arthritis
induced apoptosis
oxidative stress
cell death
endoplasmic reticulum stress
pi k akt
endothelial cells