Isotretinoin Induced Hyperlipidemia and Impact of Leptin Gene rs 7799039 Polymorphism in Safety of Acne Patients.
Amal A MohamedAlshymaa A HassnineAmr ElsayedMahmoud MontaserYasmeen IsmailAhmed El-DemeryEman SultanRania S Abdel AzizEman EldemiryRadwa HagagAmal A El KholyEman SalahPublished in: Pharmacogenomics and personalized medicine (2021)
LEP rs7799039 gene had an impact on the clinical response, lipid profile and liver enzymes in AV patients treated with oral isotretinoin. LEP rs7799039 CC genotype is predicted to be the treatment candidate for 6 month oral isotretinoin.
Keyphrases
- end stage renal disease
- ejection fraction
- genome wide
- copy number
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- genome wide identification
- gene expression
- metabolic syndrome
- adipose tissue
- patient reported outcomes
- endothelial cells
- combination therapy
- skeletal muscle
- smoking cessation