Circulating bacterial signature is linked to metabolic disease and shifts with metabolic alleviation after bariatric surgery.
Rima M ChakarounLucas MassierAnna Heintz-BuschartNedal SaidJoerg FallmannAlyce CraneTatjana SchützArne DietrichMatthias BlüherMichael StumvollNiculina MusatPeter KovacsPublished in: Genome medicine (2021)
We show that the circulating bacterial signature reflects metabolic disease and its improvement after bariatric surgery. Our work provides contaminant-aware evidence for the presence of living bacteria in the blood and suggests a putative crosstalk between components of the blood and metabolism in metabolic health regulation.