Therapeutic drug monitoring of tacrolimus and mycophenolic acid in outpatient renal transplant recipients using a volumetric dried blood spot sampling device.
Tom C ZwartSumit R M GokoelPaul J M van der BoogJohan W de FijterDina M KweekelJesse J SwenHenk-Jan GuchelaarDirk Jan A R MoesPublished in: British journal of clinical pharmacology (2018)
Tacrolimus and mycophenolic acid TDM for outpatient renal transplant recipients, based on abbreviated AUC collected with a DBS sampling device, is comparable to conventional TDM based on WB sampling. Patient training and guidance on good blood-spotting practices is essential to ensure method feasibility.