Chemical and Physical Characterisation of Macroaggregated Human Serum Albumin: Strength and Specificity of Bonds with 99m Tc and 68 Ga.
Letizia CanzianiManuela MarencoGiorgio CavenaghiGiulia ManfrinatoAngelo TagliettiAlessandro GirellaCarlo AprileGiovanna PepeLorenzo LodolaPublished in: Molecules (Basel, Switzerland) (2022)
Radiolabelling of MAA is possible with high efficiency. The nondiscriminatory MAA bonds make this drug suitable for radiolabelling with different radioisotopes or for dual labelling. This finding illustrates the need to continue investigating MAA chemical and physical characteristics to allow for secure labelling with different isotopes.