Reproducibility of lung cancer radiomics features extracted from data-driven respiratory gating and free-breathing flow imaging in [ 18 F]-FDG PET/CT.

Calculated on all pulmonary lesions, 131 out of 141 radiomics features can be used interchangeably between DDG and FB PET/CT acquisitions. Radiomics features derived from pulmonary lesions located inferior to the superior lobes are subject to greater variability as well as pulmonary lesions of smaller size.