Associations between DNA methylation and gene regulation depend on chromatin accessibility during transgenerational plasticity.

Samuel N Bogan Marie E Strader Gretchen E Hofmann

Published in: BMC biology (2023)

DNA methylation likely possesses multiple associations with gene regulation during transgenerational plasticity in S. purpuratus and potentially other metazoans, but its effects are dependent on chromatin accessibility and underlying genic features.

Keyphrases

dna methylation
genome wide
gene expression
dna damage
transcription factor
copy number
oxidative stress