Induction of epithelial-mesenchymal transition in thyroid follicular cells is associated with cell adhesion alterations and low-dose hyper-radiosensitivity.

Ankit MathurVijayakumar ChinnaduraiParam Jit Singh BhallaSudhir Chandna

Published in: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine (2023)

The study shows that induction of EMT in thyroid follicular cells may accompany increased susceptibility to low-dose ionizing radiation, which was attenuated by adaptive resistance acquired during radiation-induced transformation.

Keyphrases

low dose
epithelial mesenchymal transition
radiation induced
induced apoptosis
cell cycle arrest
cell adhesion
high dose
cell death
transforming growth factor