Login / Signup

A fungal ubiquitin ligase and arrestin binding partner contribute to pathogenesis and survival during cellular stress.

Lukas M du PlooyCalla L TelzrowConnie B NicholsCorinna ProbstNatalia Castro-LopezFloyd L WormleyJ Andrew Alspaugh
Published in: mBio (2024)
. We identified a complex of proteins responsible for adding ubiquitin groups to fungal proteins, and this complex is required for virulence. These proteins are fungal specific and might be targets for novel anti-infection therapy.
Keyphrases
  • escherichia coli
  • staphylococcus aureus
  • pseudomonas aeruginosa
  • small molecule
  • cell wall
  • antimicrobial resistance
  • mesenchymal stem cells
  • heat stress
  • dna binding
  • free survival
  • binding protein