Impact of infected and noninfected human dentine debris on bone healing in rats.
Fernanda Geraldo PappenS R XavierK J PilownicLuciane Geanini Pena Dos SantosA P N GomesA C FelixFlavio Fernando DemarcoErick Miranda SouzaPublished in: International endodontic journal (2019)
The assumption that the amount of extruded debris may negatively affect the inflammatory response of bone tissue was not validated in the present in vivo animal study. Infected dentine may trigger acute inflammatory parameters especially during the first 7 days of contact with the tissue; however, in the long term, these negative effects are mitigated.
Keyphrases
- inflammatory response
- bone mineral density
- endothelial cells
- liver failure
- soft tissue
- bone loss
- bone regeneration
- oxidative stress
- lipopolysaccharide induced
- respiratory failure
- postmenopausal women
- drug induced
- intensive care unit
- aortic dissection
- body composition
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome
- mechanical ventilation