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Comprehensive Transcriptomics Profiling of MicroRNA Reveals Plasma Circulating Biomarkers of Hypertrophic Cardiomyopathy and Dysregulated Signaling Pathways.

Lusha W LiangKohei HasegawaMatthew John MaurerMuredach P ReillyMichael A FiferYuichi J Shimada
Published in: Circulation. Heart failure (2023)
This study utilized comprehensive transcriptomics profiling with RNA sequencing in HCM, revealing circulating miRNA biomarkers and dysregulated pathways.
Keyphrases
  • single cell
  • hypertrophic cardiomyopathy
  • left ventricular
  • signaling pathway
  • epithelial mesenchymal transition
  • cell proliferation
  • induced apoptosis
  • oxidative stress
  • pi k akt