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[Management of chronic inflammatory demyelinating polyradiculoneuropathy].

Valentin LoserKatia StaedlerEglé SukockienéMarjolaine UginetRenaud A Du PasquierPatrice H LaliveMarie Théaudin
Published in: Revue medicale suisse (2024)
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is the most common chronic autoimmune neuropathy. Its management has considerably evolved over the last decade. In 2021, the diagnostic guidelines for CIDP were updated and the diagnostic criteria simplified. They enable better characterization of the electro-clinical phenotype of the disease, and emphasize supportive criteria, in particular neuro-muscular imaging. In terms of pathophysiology, the discovery of antibodies directed against antigens in the nodal and paranodal regions has given rise to the concept of autoimmune nodopathy. Finally, the preliminary results of the ADHERE study on efgartigimod have rekindled hopes of a new, effective therapy for CIDP.
Keyphrases
  • multiple sclerosis
  • drug induced
  • oxidative stress
  • high resolution
  • small molecule
  • dendritic cells
  • clinical practice
  • radiation therapy
  • body composition
  • rectal cancer
  • high intensity