Arousal characteristics in patients with Parkinson's disease and isolated rapid eye movement sleep behavior disorder.
Andreas Brink-KjaerMatteo CesariFriederike Sixel-DöringBrit MollenhauerClaudia TrenkwalderEmmanuel MignotHelge B D SorensenPoul JennumPublished in: Sleep (2022)
Patients with PD and iRBD present with abnormal arousal characteristics as scored by an automated method. These abnormalities are likely to be caused by neurodegeneration of the reticular activation system due to alpha-synuclein aggregation.