Immune checkpoints as potential theragnostic biomarkers for epithelial ovarian cancer.
Azza HabelWeili XuMariem Hadj AhmedMouna StayoussefHanen BouazizMouna AyadiAmel MezliniAnis LarbiBasma Yaacoubi-LoueslatiPublished in: The International journal of biological markers (2023)
This study has yielded a first panel of seven immune checkpoints (BTLA, CD40, CD80/B7-1, GITRL, LAG-3, TIM-3, TLR-2) associated with a higher risk of EOC and a second panel of four immune checkpoints (CD40, HVEM, PD-1, PD-L1) that may help physicians to identify EOC patients who are at high risk of developing resistance to EOC chemotherapy.