Evaluating the clinical effectiveness and safety of various HER2-targeted regimens after prior taxane/trastuzumab in patients with previously treated, unresectable, or metastatic HER2-positive breast cancer: a systematic review and network meta-analysis.

Noman ParachaAdriana ReyesVéronique DiérasIan KropXavier PivotAnder Urruticoechea

Published in: Breast cancer research and treatment (2020)

The efficacy and tolerability profiles of T-DM1 are generally favorable compared with other treatments for unresectable or metastatic HER2-positive BC.

Keyphrases

positive breast cancer
squamous cell carcinoma
locally advanced
small cell lung cancer
liver metastases
metastatic breast cancer
open label
epidermal growth factor receptor
rectal cancer
type diabetes
clinical trial
radiation therapy
newly diagnosed
skeletal muscle
drug delivery
placebo controlled
study protocol