Relationship between the distribution of intra-retinal hyper-reflective foci and the progression of intermediate age-related macular degeneration.
Aditya VermaGiulia CorradettiYe HeMuneeswar G NittalaMarco NassisiSwetha B VelagaJonathan L HainesMargaret A Pericak-VanceDwight StambolianSriniVas R SaddaPublished in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2023)
The risk of progression to late AMD appears to be significantly associated with the distribution and extent of IHRF in the outermost retinal layers. This observation may point to significant pathophysiologic differences of IHRF in inner versus outer layers of the retina.