Understanding progressive multifocal leukoencephalopathy: links between milky-way appearance and mismatch T2/FLAIR.
Emiliano Ruiz RomagnoliManuel Sliman Perez AklyLuis A MiqueliniJorge FunesTatiana GillandersCristina BesadaPublished in: The neuroradiology journal (2021)
The possible tract-dependent spread, as well as clinical and genetic, have implications on the MRI variability of progressive multifocal leukoencephalopathy. The milky-way appearance could reflect a transitional phase towards evolved lesions, the latter demonstrated by T2/fluid-attenuated inversion recovery mismatch. Both could be key magnetic resonance imaging signs to diagnose progressive multifocal leukoencephalopathy at the symptomatic stage.