Comprehensive analysis of autophagy-related gene expression profiles identified five gene biomarkers associated with immune infiltration and advanced plaques in carotid atherosclerosis.

Chi MaTaoyuan LuYanyan HeDehua GuoLin DuanRufeng JiaDongyang CaiTao GaoZhongcan ChenBinghua XueTianxiao LiYing-Kun He

Published in: Orphanet journal of rare diseases (2023)

In this study, we identified 5 hub ATGs including CASP1, CCL2, CTSD, ITGA6 and TNFSF10, which could serve as candidate diagnostic biomarkers and therapeutic targets.

Keyphrases

gene expression
dna methylation
cell death
cardiovascular disease
signaling pathway
genome wide
oxidative stress
endoplasmic reticulum stress
copy number
liver injury
type diabetes
drug induced
bioinformatics analysis