Progress on transition metal catalyzed asymmetric hydroesterification, hydrocarboxylation, and hydroamidation reactions of olefins.

Hydrocarboxylation, hydroesterification, and hydroamidation of olefins are fundamental transformations in organic synthesis. Asymmetric processes for these transformations provide an effective and straightforward approach to optically active carboxylic acids and their derivatives, which are highly useful compounds in pharmaceuticals, materials, fine chemicals, etc. This review provides a brief summary of the development of asymmetric hydroesterification, hydrocarboxylation, and hydroamidation with CO and its surrogates.