The Role of Tight Junctions in Atopic Dermatitis: A Systematic Review.

Spyridoula Katsarou Michael MakrisEfstratios VakirlisStamatios Gregoriou

Published in: Journal of clinical medicine (2023)

Dysfunction of TJs and their components, especially claudins, have a significant role in the pathogenesis and vicious circle of inflammation in AD. Discovering more basic science data regarding TJ functionality may be the key for the use of specific/targeted therapies in order to improve epidermal barrier function in AD.

Keyphrases

atopic dermatitis
oxidative stress
public health
blood brain barrier
electronic health record
single molecule
big data
wound healing