Prophylactic immunization to Helicobacter pylori infection using spore vectored vaccines.
Paidamoyo M KatsandeVan Duy NguyenThi Lan Phuong NguyenThi Kim Cuc NguyenGabrielle MillsDavid M D BaileyGraham ChristieHuynh Anh HongSimon M CuttingPublished in: Helicobacter (2023)
This study demonstrates the utility of bacterial spores for mucosal vaccination to H. pylori infection. The heat stability and robustness of Bacillus spores coupled with their existing use as probiotics make them an attractive solution for either protection against H. pylori infection or potentially for therapy and control of active infection.