Mercaptopurine-Loaded Sandwiched Tri-Layered Composed of Electrospun Polycaprolactone/Poly(Methyl Methacrylate) Nanofibrous Scaffolds as Anticancer Carrier with Antimicrobial and Antibiotic Features: Sandwich Configuration Nanofibers, Release Study and in vitro Bioevaluation Tests.
Samar A SalimElbadawy A KamounStephen EvansShahira Hussainy El-MoslamyEsmail M El-FakharanyMohamed M ElmazarA F Abdel-AzizRadwa H Abou-SalehTaher A SalaheldinPublished in: International journal of nanomedicine (2021)
Overall, the PCL: PMMA ratio and sandwich configuration imparts a tight control on long-term release profile and initial burst of 6-MP for anticancer treatment purposes.