Induction of Hepatocellular Carcinoma in Conventional Domestic Swine Using N-Diethylnitrosamine and Phenobarbital.

Angela Giselvania Vetnizah Juniantito Heri Wibowo Trifonia Pingkan Siregar Soehartati Argadikoesoema Gondhowiardjo

Published in: Cancer management and research (2024)

This study successfully generated HCC in conventional domestic swine with a DENA and PB combination. This investigation required at least 15 months to develop tumors. This model will be beneficial for future investigations of HCC in large animals.

Keyphrases

heavy metals