Revisiting cytomegalovirus serology in allogeneic hematopoietic cell transplant recipients.
Vera PortilloStavroula Masouridi-LevratLéna RoystonSabine YerlyManuel SchiblerMaria MappouraSarah MorinFederica GiannottiAnne-Claire MamezChristian van DeldenYves ChalandonDionysios NeofytosPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)
One out of four allo-HCT CMVR + may be falsely flagged as R+, with significant impact on donor selection and prophylaxis administration. A 2-step approach including CMV-serology testing at hematologic malignancy diagnosis in allo-HCTR candidates and careful review of pretransplant CMV IgG-titers may help correctly classify CMV-serology status.