Successful treatment with assisted automated peritoneal dialysis using 4.25% glucose dialysate for an elderly patient with refractory heart failure.
Naohiro TodaRyosuke IwakiKaori OishiYuichi TakasuToshiyuki KomiyaPublished in: CEN case reports (2020)
Refractory heart failure is a major cause of mortality and hospitalization, and peritoneal dialysis (PD) is one of the options for controlling volume overload. Although high glucose dialysate enables a large amount of ultrafiltration, the use of 4.25% glucose dialysate is generally avoided, because high glucose exposure leads to peritoneal damage. Here, we describe a patient who was successfully treated with assisted automated PD using 4.25% glucose dialysate for refractory heart failure. An 84-year-old woman developed heart failure due to severe mitral regurgitation with a low left-ventricular ejection fraction of 30%, and also developed progressive kidney deterioration. She had been refractory to diuretics and repeatedly hospitalized. PD was started to treat refractory heart failure. Since it was difficult for her to change the dialysis bags by herself, assistance with her PD from her family was needed. The use of 4.25% glucose dialysate markedly increased ultrafiltration and improved her condition. In addition, automated PD (APD) using 4.25% glucose dialysate enabled her family to have a break from PD once every 4 days. Thereafter, she had no episodes of hospitalization due to heart failure for approximately 18 months after her discharge.
Keyphrases
- peritoneal dialysis
- heart failure
- end stage renal disease
- left ventricular
- high glucose
- cardiac resynchronization therapy
- endothelial cells
- blood glucose
- ejection fraction
- acute heart failure
- machine learning
- deep learning
- atrial fibrillation
- case report
- type diabetes
- acute myocardial infarction
- cardiovascular disease
- coronary artery disease
- hypertrophic cardiomyopathy
- skeletal muscle
- early onset
- blood pressure
- cardiovascular events
- drug induced
- transcatheter aortic valve replacement