Explore the shared molecular mechanism between dermatomyositis and nasopharyngeal cancer by bioinformatic analysis.
Xiuqin ZhongJingjing ShangRongwei ZhangXiuling ZhangLe YuHaitao NiuXin-Wang DuanPublished in: PloS one (2024)
Our research discovered pivot genes between DM and NPC. Viral gene replication and response to type I interferon may be the crucial bridge between DM and NPC. By regulating hub genes, MiR-146a will provide new strategies for diagnosis and treatment in DM complicated by NPC patients. For individuals with persistent viral replication in DM, screening for nasopharyngeal cancer is necessary.
Keyphrases
- papillary thyroid
- genome wide
- end stage renal disease
- genome wide identification
- sars cov
- squamous cell
- glycemic control
- ejection fraction
- bioinformatics analysis
- newly diagnosed
- cell proliferation
- long non coding rna
- chronic kidney disease
- prognostic factors
- squamous cell carcinoma
- dendritic cells
- peritoneal dialysis
- type diabetes
- dna methylation
- long noncoding rna
- rheumatoid arthritis
- patient reported outcomes
- insulin resistance
- transcription factor
- systemic lupus erythematosus
- respiratory tract