Class switching is differentially regulated in RBC alloimmunization and vaccination.
Anupam PrakashJelena MedvedAbhinav ArnejaConrad NiebuhrAndria N LiSoraya TarrahAlexis R BosciaEmily D BurnettAanika SinghJuan E SalazarWenhao XuManjula SanthanakrishnanJeanne Elise HendricksonChance John LuckeyPublished in: Transfusion (2023)
Our results show that anti-RBC class-switching occurs via alternate mechanisms when compared with the well-studied immunogen alum vaccination.