Intravenous Thrombolysis in Patients With Ischemic Stroke Aged ≥90 Years: A Cohort Study From the TRISP Collaboration.
Valerian L AltersbergerNorman RuscheNicolas Martinez-MajanderChristian HametnerJan F ScheitzHilde HénonMaria Luisa Dell'AcquaDavide StramboJeffrey StolpMirjam Rachel HeldnerIlaria GrisendiDejana R JovanovicYannick BejotAlessandro PezziniRonen R LekerGeorg KägiSusanne WegenerCarlo Walter CeredaErik LindgrenGeorge NtaiosInes PiotAlexandros A PolymerisPhilippe A LyrerSilja RätyGerli SiboltMarjaana TiainenMiriam HeyseHebun ErdurOlfa KaaouanaVisnja PadjenMaria Luisa ZeddeMarcel ArnoldPaul J NederkoornPatrik MichelGuido BigliardiAndrea ZiniCharlotte CordonnierChristian H NoltePeter Arthur RinglebSami CurtzeStefan T EngelterHenrik Gensickenull nullPublished in: Stroke (2022)
The probability of symptomatic intracranial hemorrhage after IVT in very elderly patients with stroke did not exceed that of their younger counterparts. The higher probability of death and poor functional outcome during follow-up in the very elderly seems not to be related to IVT treatment. Very high age itself should not be a reason to withhold IVT.