Copper Deficiency: Causes, Manifestations, and Treatment.
Marco AltarelliNawfel Ben-HamoudaAntoine SchneiderMette M BergerPublished in: Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition (2019)
Deficiency is more frequent than previously recognized, probably because of changing nutrition patterns but also because of some treatments that have become very common such as bypass bariatric surgery and, in acute medicine, prolonged continuous renal replacement therapy. The patients may present with severe hematologic and neurologic complications that go untreated because copper deficiency was not considered in the differential diagnosis: These complications often need active intravenous repletion with doses 4-8 times the usual nutrition recommendations.
Keyphrases
- bariatric surgery
- end stage renal disease
- replacement therapy
- physical activity
- chronic kidney disease
- ejection fraction
- newly diagnosed
- acute kidney injury
- prognostic factors
- liver failure
- drug induced
- weight loss
- early onset
- high dose
- intensive care unit
- obese patients
- low dose
- respiratory failure
- oxide nanoparticles
- hepatitis b virus
- mechanical ventilation