Genome-Wide Genetic Associations Prioritize Evaluation of Causal Mechanisms of Atherosclerotic Disease Risk.
Thomas QuertermousDaniel Yuhang LiChad S WeldyMarkus RamsteVinod ScariaJoão P MonteiroWenduo GuMatthew D WorssamBrian T PalmisanoChong Y ParkPaul ChengPublished in: Arteriosclerosis, thrombosis, and vascular biology (2024)
Genome-wide association studies represent a paradigm shift in the study of cardiovascular disease, providing identification of genes, cellular phenotypes, and disease pathways that empower the future of targeted drug development.