Acute progressive paravascular placoid neuroretinopathy with negative-type electroretinography in paraneoplastic retinopathy.
Fred K ChenAvenell L ChewDan ZhangShang-Chih ChenEnid ChelvaErandi ChandrasekeraEleanor M H KoayJohn ForresterSamuel McLenachanPublished in: Documenta ophthalmologica. Advances in ophthalmology (2017)
A spectrum of autoreactive anti-retinal antibodies is associated with a unique phenotype of acute progressive paravascular placoid neuroretinopathy resulting in degeneration of photoreceptor cells, inner retinal dysfunction and classic electronegative ERG in paraneoplastic retinopathy. Detailed clinical, functional and immunological phenotyping of paraneoplastic retinopathy illustrated the complex mechanism of paraneoplastic syndrome.
Keyphrases
- liver failure
- optical coherence tomography
- multiple sclerosis
- respiratory failure
- diabetic retinopathy
- induced apoptosis
- drug induced
- oxidative stress
- optic nerve
- high throughput
- intensive care unit
- cell proliferation
- endoplasmic reticulum stress
- extracorporeal membrane oxygenation
- single cell
- mechanical ventilation