Distinct molecular etiologies of male and female hepatocellular carcinoma.

Heini M NatriMelissa A WilsonKenneth H Buetow

Published in: BMC cancer (2019)

Sex-stratified analyses detect sex-specific molecular etiologies of HCC. Overall, our results provide new insight into the role of inherited genetic regulation of transcription in modulating sex-differences in HCC etiology and provide a framework for future studies on sex-biased cancers.

Keyphrases

signaling pathway
transcription factor
current status
gene expression
copy number