Intra-Articular Injection of Autologous Micro-Fragmented Adipose Tissue for the Treatment of Knee Osteoarthritis: A Prospective Interventional Study.
Yang YuQunshan LuSonglin LiMingxing LiuHouyi SunLei LiKaifei HanPeilai LiuPublished in: Journal of personalized medicine (2023)
Autologous MF-AT improves knee function and relieves pain with no adverse events. However, the improved knee function was not sustained, with the best results occurring 9-12 months after injection and the cartilage regeneration remaining to be investigated.
Keyphrases
- knee osteoarthritis
- adipose tissue
- bone marrow
- stem cells
- total knee arthroplasty
- chronic pain
- cell therapy
- platelet rich plasma
- ultrasound guided
- insulin resistance
- pain management
- high fat diet
- neuropathic pain
- type diabetes
- mesenchymal stem cells
- spinal cord
- metabolic syndrome
- anterior cruciate ligament
- skeletal muscle
- postoperative pain
- atomic force microscopy
- extracellular matrix
- anterior cruciate ligament reconstruction
- high speed
- single molecule
- wound healing