Association of long-term hyperglycaemia and insulin resistance with brain atrophy and cognitive decline: A longitudinal cohort study.
Ji Hee YuRegina E Y KimSo Young ParkDa Young LeeHyun Joo ChoNam Hoon KimHye Jin YooJi A SeoSin Gon KimKyung Mook ChoiSei Hyun BaikChol ShinNan Hee KimPublished in: Diabetes, obesity & metabolism (2023)
Long-term hyperglycaemia was a major independent factor associated with rapid cognitive decline in middle-aged adults with diabetes. Maintaining ideal glucose levels in diabetes at midlife might prevent later rapid cognitive decline.